The global MicroRNA (miRNA) market was valued at USD 1,230.3 million in 2022 and is projected to grow at a revenue CAGR of 19.9% during the forecast period. The market growth is primarily driven by the increasing adoption of miRNA as a biomarker.
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MiRNAs are small non-coding RNA molecules that play a crucial role in regulating gene expression and various biological processes. Due to their characteristics, such as ease of detection and resistance to degradation, miRNAs have emerged as potential biomarkers for diseases like cancer, cardiovascular disease, and neurological disorders. They are used for disease diagnosis by detecting changes in miRNA expression levels in body fluids such as blood, urine, or saliva. Furthermore, miRNAs are utilized to monitor disease progression and assess the effectiveness of treatments. These applications of miRNAs as biomarkers contribute significantly to the revenue growth of the market.
Major companies in the global market report include Merck KGaA, Horizon Discovery Ltd, Synlogic, QIAGEN, GeneCopoeia, Inc, New England Biolabs, Quantabio, NanoString, BioGenex, SeqMatic LLC.
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The rising demand for Next-Generation Sequencing (NGS) is another factor driving market growth. NGS is a high-throughput DNA sequencing technology that enables rapid and accurate sequencing of large amounts of DNA. It generates millions or billions of DNA sequence reads in a single run, facilitating the generation of vast amounts of data. NGS technologies offer ultra-high throughput, scalability, and speed, making them valuable tools in various applications such as gene expression analysis, genetic variation analysis, and genome assembly and annotation. Researchers can simultaneously sequence multiple samples, reducing the number of experiments and resources required. The decreasing cost of DNA sequencing, driven by the development of NGS technologies, has made it more affordable for researchers to generate large amounts of sequencing data. These factors contribute to the demand for NGS and drive revenue growth in the miRNA market.
An example of collaboration in the field of NGS-based cancer diagnostics is the partnership between The Medical Device Innovation Consortium (MDIC) and PerkinElmer’s Horizon Discovery. They aim to create and manufacture Somatic Reference Samples (SRSs) to enhance the validation of NGS-based cancer diagnostics. This collaboration focuses on improving cancer testing using NGS technology.
Overall, the increasing adoption of miRNA as a biomarker and the rising demand for NGS technology are key drivers of revenue growth in the global miRNA market.
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Driver:
The rising demand for microarray analysis tools is a primary factor driving revenue growth in the miRNA market. Microarray analysis tools are used to analyze the expression levels of microRNAs (miRNAs) in different samples or conditions. These tools enable researchers to simultaneously measure the expression levels of hundreds or thousands of miRNAs in a single experiment, providing a high-throughput method for studying miRNA expression. By analyzing multiple samples, microarray analysis tools reduce the number of experiments needed and save time and resources. They have high accuracy rates, allowing the detection of small changes in miRNA expression levels, making them reliable for measuring miRNA expression. Moreover, microarray analysis tools enable the comparison of miRNA expression profiles between different samples or conditions, helping researchers identify differentially expressed miRNAs potentially involved in specific biological processes or diseases. All these factors contribute significantly to the revenue growth of the market.
A microRNA (miRNA) is a small, single-stranded RNA molecule found in animals, plants, and various viruses. miRNAs play essential roles in post-transcriptional regulation of gene expression and RNA silencing. They regulate vital cellular functions such as cell differentiation, proliferation, apoptosis, and are involved in various physiological processes, development, and pathological conditions like viral infections, autoimmune diseases, and carcinogenesis. miRNAs are abundant in various mammalian cell types. Researchers use microRNA sequencing, which utilizes next-generation DNA sequencing technology, to study miRNA isoforms, tissue-specific expression patterns, and their associations with diseases.
Restraint:
One of the main limitations of using miRNA as therapeutics is the risk of off-target effects, where a miRNA binds to unintended mRNA targets and regulates their expression. This can lead to unintended consequences and negative side effects. miRNAs often have multiple targets and can regulate the expression of multiple genes, making it challenging to predict the exact effects of modulating their activity. This complexity poses difficulties in utilizing miRNA as a therapeutic agent. Another limitation is the delivery of miRNA to the appropriate cells and tissues in the body. miRNA is sensitive to degradation and can be easily lost or damaged during delivery, which can limit its effectiveness. These factors, including the risk of off-target effects and challenges in delivery, may restrain revenue growth in the miRNA market.
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For the purpose of this report, Reports and Data has segmented the global fibrinogen concentrate market based on type, application, and region:
Products Outlook (Revenue, USD Million; 2019-2032)
- Instruments
- Kits, Reagents & Consumables
- Insolation & Purification
- Quantification & Detection
- Functional Analysis
- Others
Research & Tools Outlook (Revenue, USD Million; 2019-2032)
- qRT-PCR
- Biomarkers
- Next Gen Sequencing (NGS)
- Microarray Analysis Tools
- Functional Analysis Tools
- Extraction Tools
- Others
Application Form Outlook (Revenue, USD Million; 2019-2032)
- Cancer
- Infectious Diseases
- Immunological Disorder
- Cardiovascular Disease
- Neurological Disease
End-use Outlook (Revenue, USD Million; 2019-2032)
- Academic & Research Institutes
- Biopharmaceutical Companies
- CRO
- Diagnostic Centers
Regional Outlook (Revenue, USD Million; 2019-2032)
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
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